Guanidine HCl at millimolar concentrations, is able to causes efficient loss of the normally stable PSI element from yeast cells 5 mM Guanidine HCl in growth media cures PSI and other prions of yeast 5 mM Guanidine HCl significantly reduces Hsp104mediated basal and acquired thermotolerance by 30fold and 50 fold, respectively Guanidine HCl also reduces the Its hydrochloride salt is highly watersoluble and is the usual article of commerce The free base is extremely toxic, as shown in the hazard information table Guanidine was discovered in nature in the late 19th century In 1907, a German patent was awarded to Italian chemist Celso Ulpiani for the reaction of dicyanamide with strong acid to produce guanidinePowerful protein denaturant Pricing Match Criteria Product Name, Keyword NCYCLOOCTYL
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